Webinar: Understanding ASDs- How phase diagrams guide stability, manufacturing and release
Why does an API remain amorphous during storage, yet fail to release as expected during dissolution? These questions share a
Predicting pH-Dependent Solubility, Solid Form, and Polymer Release with PC-SAFT
Most drug candidates entering development are poorly soluble, which limits their bioavailability. Over the past few decades, several formulation techniques
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Case studies, Science
The Glass Transition Line: The Kinetic Lock in Your ASD Phase Diagram
The glass transition (Tg) line is key to understanding and designing ASDs. In ASD phase diagrams, it is shown alongside
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Insights, Science
Spray Drying ASDs: The Formulator’s Question Playbook
Spray drying is the leading method for producing amorphous solid dispersions (ASDs). It is also the process in which many
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Products, Science
How amofor Helped Bend Bioscience Model a Core-Shell Inhalation Particle for Lung Cancer Therapy
A spray-dried inhalation particle is a few microns wide. It has to carry an amorphous API to the lungs, survive
ASD Phase Diagrams: The Root of Every Drug Formulation Project
Almost every amorphous solid dispersion (ASD) is a metastable system: a drug in a polymer matrix in a high‑energy amorphous
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Products, Science
How Real-World Drug Formulation Challenges Shape amofor’s Internal Research Roadmap
If you work in drug formulation, you know this problem: a formulation looks fine on paper, but a small change
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Insights
Product Update: Big Data Fitting Is Now Built into SOLCALC
SOLCALC helps formulators build a predictive digital twin of their drug formulation. Thus, decisions like polymer or solvent choice can
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Products, Solcalc
In Silico Screening of Greener, Non-Toxic Solvent Systems for Spray Drying of ASDs
For decades, spray drying has relied on a small set of “gold-standard” solvents. If you wanted high solubility, fast evaporation,
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Products, Science
Our 2025 Milestones and a Look Ahead to 2026
When we founded amofor more than six years ago, most of what we did lived in equations, theories, and model
Our 2025 Milestones and a Look Ahead to 2026 Read More »
Insights