
Key experiments
Only few experiments with small quantities of the expensive active ingredient are required to characterize molecule-specific interactions with other compounds.
Predict long-term stability
The physical stability of amorphous formulations against crystallization and amorphous phase separation is predicted with this innovative quality-by-design approach.
Results of long-term stability tests enduring years are obtained within days.
In-silico calculations
Advanced in-silico modeling tools taking into account the specific intermolecular interactions reveal the optimal formulation and production process windows.
Designing production processes
Identify optimal solvents, solvent mixtures, processing temperatures, drying conditions (spray drying/ coating) for the formulation are assesible without any further screenings.

Featured Publications

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Gaining fundamental molecular understanding is a true benefit!
Find the best excipients for your formulation
Determine safe design spaces of the production process
Reduce material consumption of expensive active ingredients
Save time – obtain the results of long-term stability tests even before conducting them
Decrease the number of screening experiments
Understand the influence of critical quality attributes on formulation stability
Thermodynamic modeling is a gamechanger for everybody in formulation development
Formulation leads
Excipient selection
Formulation compositions
Stability derisking
Solid state scientists
Purification issues
Oiling-out prevention
Crystallization design
Solid form stability (Polymorphs, salts, hydrates, solvates, cocrystals…)
Quality managers
Controling sensitivity of process on product quality
Process designers
Manufacturing process (Spray drying, crystallization, precipitation, hot melt extrusion design…)
Design spaces and operation windows
We love challenging molecules.
The crystallization of the molecule fails?
Unexpected challenges everywhere across the development?
The molecule has a complex structure, high molar mass and many complex functional groups?
Perfect. Lets get started.