Getting drug molecules faster formulated
Combining few key experiments with in-silico predictions is the perfect way towards the optimal formulation for your active ingredient

Key experiments

Only few experiments with small quantities of the expensive active ingredient are required to characterize molecule-specific interactions with other compounds.

Predict long-term stability

The physical stability of amorphous formulations against crystallization and amorphous phase separation is predicted with this innovative quality-by-design approach.

Results of long-term stability tests enduring years are obtained within days.

In-silico calculations

Advanced in-silico modeling tools taking into account the specific intermolecular interactions reveal the optimal formulation and production process windows.

Designing production processes

Identify optimal solvents, solvent mixtures, processing temperatures, drying conditions (spray drying/ coating) for the formulation are assesible without any further screenings.

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Gaining fundamental molecular understanding is a true benefit!

Find the best excipients for your formulation

Determine safe design spaces of the production process

Reduce material consumption of expensive active ingredients

Save time – obtain the results of long-term stability tests even before conducting them

Decrease the number of screening experiments

Understand the influence of critical quality attributes on formulation stability

Thermodynamic modeling is a gamechanger for everybody in formulation development.

Formulation leads

Excipient selection

Formulation compositions

Stability derisking

Solid state scientists

Purification issues

Oiling-out prevention

Solid form stability (Polymorphs, salts, hydrates, solvates, cocrystals…)

Process designers

Manufacturing process (Spray drying, crystallization, precipitation, hot melt extrusion design…)

Design spaces and operation windows

Crystallization design

Quality managers

Controling sensitivity of process on product quality

We love challenging molecules.

The crystallization of the molecule fails?

Unexpected challenges everywhere across the development?

The molecule has a complex structure, high molar mass and many complex functional groups?

Perfect. Lets get started.

We are curious about your challenges in formulation development.

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